Separate Critical Periods Exist for Testosterone-Induced Differentiation of the Brain and Genitals in Sheep

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Separate critical periods exist for testosterone-induced differentiation of the brain and genitals in sheep.

Sheep exposed to testosterone during a critical period from gestational day (GD) 30 to GD 90 develop masculine genitals and an enlarged male-typical ovine sexually dimorphic nucleus of the preoptic area (oSDN). The present study tested the hypothesis that separate critical periods exist for masculinization of these two anatomical end points. Pregnant ewes were treated with testosterone propiona...

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ژورنال

عنوان ژورنال: Endocrinology

سال: 2011

ISSN: 0013-7227,1945-7170

DOI: 10.1210/en.2010-1445